Patients with chronic granulomatous disease (CGD) get recurrent infections with a variety of bacterial and fungal pathogens as a consequence of phagocyte defects in production of antimicrobial reactive oxygen metabolites. Patients with CGD often present with clinical syndromes, such as pneumonia or lymphadenitis, for which no credible pathogen is identified, leading to empirical broad-spectrum antibacterial and antifungal therapy. The question beleaguering the clinician in this scenario is whether the patient is infected with a common microbe (e.g., Aspergillus fumigatus, Nocardia asteroides, Staphylococcus aureus) that has eluded detection, or a novel fastidious microbe.
Towards a New Ethnohistory is a refreshing departure from the current Canadian literary crisis beleaguering my colleagues. Some scholars have entered a paralytic state in the wake of the exposure of CanLit's ideological motivations. This is not the case with the early-career scholars presented in this uplifting and rigorous volume edited by Keith Thor Carlson, John Sutton Lutz, David M. Schaepe, and Naxaxalhts'i. Settler scholars working on Indigenous anthropology and ethnography have had to reckon with the colonial investments of their fields much earlier than scholars in literary studies. Towards a New Ethnohistory is an illustrative example of criticism that demonstrates the complexity and stickiness of wrangling with colonial desire and epistemological difference. It also proves that the rewards for doing so are great. This collection models the ways in which research can provide a way to establish respectful and reciprocal relationships between different cultural communities. In... 041b061a72